Question:
Pro-inflammatory cytokines involved in the pathogenesis of RHEUMATOID ARTHRITIS secreted by synovial macrophages that stimulates synovial cells to proliferate and synthesize collagenase (degrades cartilage, stimulates bone resorption & inhibits proteoglycan synthesis)
Author: LEIGHTON DWIGHT OBILLOSAnswer:
IL-1 (Interleukin) and TNF-α (Tumor Necrosis Factor)
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