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From course:

PHARMACOLOGY 1

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Question:

Pro-inflammatory cytokines involved in the pathogenesis of RHEUMATOID ARTHRITIS secreted by synovial macrophages that stimulates synovial cells to proliferate and synthesize collagenase (degrades cartilage, stimulates bone resorption & inhibits proteoglycan synthesis)

Author: LEIGHTON DWIGHT OBILLOS



Answer:

IL-1 (Interleukin) and TNF-α (Tumor Necrosis Factor)


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