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DRUG DISCOVERY DEVELOPMENT (DDD)
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Question:
SUBGROUP ANALYSIS Potential causes of deceptive findings:
Author: LEIGHTON DWIGHT OBILLOSAnswer:
1 TRIAL WAS NOT DESIGNED TO ASSURE THERE WAS ADEQUATE SAMPLE SIZE for the subgroup analysis 2 Potentially CONFOUNDING VARIABLES were NOT MEASURED or controlled 3 INSUFFICIENT THEORETICAL UNDERPINNINGS for the test
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