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Pharmacology

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Question:

What are some of the CYP-dependent oxidation reactions?

Author: H K



Answer:

Alipathic Hydroxylation (barbiturates, digotoxin, cyclosporin) Aromatic hydroxylation (propranolol, phenytoin) N-Dealkylation (lidocaine) O-Dealkylation (Codeine) S-oxidation (Cimetidine) N-Oxidation (Quinidine) Desulfuration (thiopental) Epoxide formation (carbamezipine)


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Author

H K
H K