Question:
What are irreversible manifestations of hemochromatosis?
Author: H KAnswer:
Liver (cirrhosis/carcinoma -most common cause of death) Pituitary (GnRH insufficiency->secondary hypogonadism) Pancreas (DM 30-60%) Thyroid (hypothyroid) Genitalia (primary hypogonadism) Joints (arthropathy (20-70%), pseudogout)
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