Question:
How is dx of hemochormatosis?
Author: H KAnswer:
Labs (serum iron 180-300 micg/dl or 32-54 micmol/dl, transferrin 45-100%, ferritin men 300-3000, women 250-3000) Liver cytology (iron stain 3+ 4+, iron concentration 3000-30000 micg/g, iron index age>1.9). Genetic (HFE mutation analysis homo or hetero) Radiology (CT&MRI not reliable for low iron deposits , newer MRI better sensitivity magnetic susceptibility)
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