What are consequences of ischemia?

➢Complete and extensive ischemia will be responsible for complete necrosis of the ischemic area: infarction, softening, gangrene. ➢Incomplete and transient ischemia will be accompanied by intense but transient pain occurring during the ischemic phase, and to which various semiological terms correspond: intermittent claudication of a lower limb/stress angina/intestinal angina ➢Incomplete and chronic ischemia will lead to the appearance of atrophy (with apoptosis of the most functional cells) with progressive replacement of the tissue by fibrosis (e.g. stenosis of the renal artery responsible for atrophy and fibrosis of the kidney).