How is histogenesis of atherosclerosis?

1. Thrombogenic Theory 2. "Aggression" Theory 3. Theory of intimal myocyte multiplication ➢Atherosclerosis is a complex disease involving multiple exogenous and interfering with each other and resulting in a common lesion of lipidoprotidoglucidic and macrophage infiltration of the arterial wall, with sclerosis. ➢Atherosclerosis is considered to be a chronic inflammatory response of the wall to an initial endothelial attack, the progression of which would be maintained by interactions between plasma lipoproteins, monocyte-macrophages, T lymphocytes and the constituents of the arterial wall. In fact, cells inflammatory processes are present within the lesions, underscoring the role of the inflammation in lesional development. In addition, inflammatory phenomena are also implicated in the occurrence of complications