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Rheumatology

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Question:

What are extrapulmonary clinical manifestations of sarcoidosis (Musculoskeletal and Dermatologic)?

Author: H K



Answer:

Musculoskeletal (4-38%, arthropathy [oligoarthritis, good prognosis in case of Loefgren syndrome, rarely chronic or deforming, dactylitis and tenosynovitis], Bone lesions [cystic, lytic, sclerotic, focal, osteopenia/osteoporosis], muscular disease, vasculitis) Loefgren syndrome [triad hilar adenopathy, acute arthritis/arthralgia often ankles bilateral, erythema nodosum. Usually self-limiting and good prognosis) Dermatological (30%, maculopapular eruptions [nose, lips, eyelids, forehead, back of neck], nodular lesions [face, trunk, extensors of limbs], lupus pernio [violent discoloration of nose/cheeks], erythema nodosum [panniculitis], atypical [ulcer, psoriasis, hypopigmentation.])


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H K
H K