PHARMCARE 5: (Different Study Designs for Different
Questions)

1 Incidence of common adverse events
potentially due to an intervention?

2 Incidence of rare or delayed adverse
events potentially due to an intervention?

Question

(Different Study Designs for Different 
Questions)

1 Incidence of common adverse events 
potentially due to an intervention?

2 Incidence of rare or delayed adverse 
events potentially due to an intervention?

LEIGHTON DWIGHT OBILLOS · Accepted Answer

.

1 RCTs, nested case-control studies, nof-1 trial for 
particular patients, surveillance, registries

2 Surveillance; registries; n-of-1 trial for 
particular patients; large, long-term RCT if 
feasible

(Different Study Designs for Different Questions) 1 Incidence of common adverse events potentially due to an intervention? 2 Incidence of rare or delayed adverse events potentially due to an intervention?