Question:
What is infective aortitis?
Author: H KAnswer:
• Infective aortitis may result from direct invasion of the aortic wall by bacterial pathogens such as Staphylococcus, Streptococcus, and Salmonella or by fungi. • These bacteria cause aortitis by infecting the aorta at sites of atherosclerotic plaque. • Bacterial proteases lead to degradation of collagen, and the ensuing destruction of the aortic wall leads to the formation of a saccular aneurysm referred to as a mycotic aneurysm • The pathologic characteristics of the aortic wall include acute and chronic inflammation, abscesses, hemorrhage, and necrosis. CT and MRI dx, Tx Abx and surgical removal and revascularization of lower extremitis with uninfective tissue.
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