Question:
What is Hodgkins lymphonma?
Author: H KAnswer:
• Cell of origin: germinal centre B-cell • Reed-Sternberg cells (or RS variants) in the affected tissues • Most cells in affected lymph node are polyclonal reactive lymphoid cells, not neoplastic cells Epidemio: • less frequent than non-Hodgkin lymphoma • overall M>F • peak incidence in 3rd decade
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Author
H K