Question:
What are examples of antitumor abs action on cancer?
Author: H KAnswer:
HER2: Human Epithelial Growth Factor Receptor 2 Herceptin: anti-HER-2: - Effector function: ADCC - EGF antagonist: inhibits cell proliferation Tumor cells secrete VEGF to induce angiogenesis. Anti-VEGF antibodies: - Block VEGF-VEGFR interaction - Inhibit angiogenesis - Induce tumor hypoxia
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Author
H K