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Clinical Immunology

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Question:

What are some examples of Abs indications in cancer immunotherapy?

Author: H K



Answer:

Haematological tumors — Non-Hodgkin B cell lymphomas (CD20) — Myeloid acute leukemia (CD33) — Chronic lymphocytic leukemia (CD52) Solid tumors: — breast cancer (Her 2 = ErbB2) — Melanoma, colorectal cancer — Non-small cell lung cancer (NSCLC): VEGF — Squamous cell carcinoma of the head and neck (SCCHN) Less than 15 monoclonal antibodies approved by the FDA for cancer therapy in 2012 A tremendous increase in the use of monoclonal antibodies for cancer therapy in recent years


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H K
H K