Before administering local anesthetic to a child, the maximum dose based on the child’s weight should be calculated to help prevent inadvertent overdose. There are no significant differences in the response to local anesthetics between younger and older adults, and the doses required for each block are the same regardless of patient age. However, it is prudent to stay well below the maximum recommended doses in elderly patients who often have some compromise in liver function. Because some degree of cardiovascular compromise may also be expected in elderly patients, reducing the dose of epinephrine may be prudent. Previous recommendations, now known to be wrong, precluded the use of specific local anesthetics in patients who are susceptible to MH. Today, it is well accepted that all local anesthetics are safe for these patients.