Trimethoprim: -Class -Pregnancy -Interactions -Blood disorder

-Anti-folate, antibiotic -Teratogenic in pregnancy (especially in 1st trimester) – ACEi + Trimethoprim = increased risk of hyperkalaemia – Methotrexate + Trimethoprim (both anti-folates) = increased risk of haematological toxicity -Can cause blood disorders- seek immediate medical attention if symptoms such as fever, sore throat, rash, mouth ulcers, purpura, bruising or bleeding develop