Warfarin: -Class -Interactions -Monitoring -Vitamin K

-Anticoagulant – Has many interactions with drugs and food – Examples: cranberry juice, pomegranate juice, alcohol, foods high in vit K, amiodarone, fluoroquinolones, metronidazole, phenytoin, omeprazole, carbamazepine, etc. – Requires regular INR monitoring – INR target for warfarin patients is usually between 2-3 – Interacts with vitamin K- vit K counteracts effects of warfarin + lowers INR (can be used if INR is too high)